PROJECTS | ETC

Collaboration Opportunities

The Enabling Technologies Consortium regularly issues Requests for Information and Requests for Proposals to solicit interest in collaborating on high-value opportunities to deliver innovative technologies with a compelling business case. Check back regularly to see our current opportunities, or subscribe for notifications regarding new Requests for Information and Requests for Proposals.

PROPOSALS UNDER REVIEW

Robust Sensors

ETC is seeking a partner to deliver a sensitive and robust in-line monitoring system that matches user requirements based upon past industry experience using LIF, XRF, and LIBS. Read more in the Request for Information.

Nov 4, 2019

Dry Modeling

The ETC is seeking a partner to develop a widely accessible module for modeling particle attrition during agitated drying. Read more in the Request for Information.

Jul 13, 2020

Organic Electrochemical Reactors

The ETC is seeking a partner to design and build lab and manufacturing scale electrochemical reactors that meet the safety, robustness and productivity needs of the pharmaceutical industry. Request for Information.

Jul 16, 2020

PROJECTS IN EXECUTION

Dec 1, 2016

COMPLETED PROJECTS

Next-Generation Prep SFC Instrumentation

UHPLC-DAD Spectral Deconvolution

For this project ETC is seeking potential collaborators to develop UV spectral deconvolution capabilities for UHPLC-DAD instrumentation. Read more in the Request for Information.

Oct 22, 2018

Cohesive Powder Feeding Modeling

ETC is seeking a partner to collaborate on the development of a industrially implementable model for cohesive power feeding to reduce experimental work and material consumption to predict feeding performance of cohesive powders. Read more in the Request for Proposals.

Oct 7, 2020

Development and Implementation of a Powder Feeding System to Feed Poor Flowing Materials at Low Rates

ETC is seeking a partner to collaborate on the development of a industrially implementable feeding device capable of processing smaller batch sizes at low total mass flows for use during development and commercial manufacturing. Read more in the Request for Proposals.

Oct 7, 2020

Universal Liquid Chromatography Detector

ETC is seeking to solicit understanding of what universal liquid chromatography detector technologies are currently being developed within academia and/or industry with a view to either (i) partnering with the group to evaluate the instrument (ii) provide cross-industry insight into any current design or (iii) initiate the development of a new technology which meets the groups requirements. Read more in the Request for Proposals.

Oct 4, 2021

Next Generation Capture

ETC is seeking a partner to deliver a module that would enable a platform to interface with wearable devices that could be worn by scientists inside laboratories to enhance and complement our ability to capture information from experiments. Read more in the Request for Information.

Dec 2, 2019

Crystal Morphology

ETC is seeking a partner to collaborate on development of a Crystal Morphology Prediction Tool. Read more in the Request for Information.

Dec 2, 2019

Compact HPLC

The ETC is seeking companies interested in supplying a viable commercial compact HPLC system. This technology, combined with existing automated sample extraction and dilution systems, would enable hood-mounted on-line characterization of chemical processes during development and scale-up in pharmaceutical, commodity, and specialty chemical laboratories. Read more in the Request for Information.

Nov 4, 2019

Development of a Solid Formulation Screening Workstation

ETC is seeking a partner to collaborate on the development of a solid formulation screening workstation. Read more in the Request for Information.

Feb 24, 2021

Colonic Absorption: Preclinical Characterization for Better Translation to Humans

ETC is seeking a partner to collaborate on characterization of Colonic Absorption that can facilitate implementation of Extended Release (ER) at early phase of drug development and thereby impact overall timeline of development. Read more in the Request for Information.

Feb 24, 2021

Automated Visible Particles Analytical Instrument

ETC is seeking a partner to collaborate on the development of a visible particle analytical instrument. Read more in the Request for Information.

Jul 19, 2021

In this project, desired hardware and software requirements and performance criteria collected from a cross-pharmaceutical group of SFC users will be shared with potential instrument providers, in the hope of identifying partners interested in developing, optimizing, and/or commercializing the "next-generation" of preparative SFC instrumentation collaboratively. Read More about our Request for Information and submit your response. You can also read the press release.

Online UHPLC Sampler

ETC is seeking companies interested in supplying a vendor-supported online sampling system with integrated liquid chromatographic (LC) analysis employing a low volume, probe-based sampling system capable of repeated automated sampling with the ability to perform direct sample injection for LC analysis for any desired number of reaction time points. Read the Request for Information.

For this project ETC is seeking potential collaborators to develop a cost-effective, user-friendly platform focused solely on reliable solubility measurement that can be operated in “walk-up” mode to deliver accurate, reproducible solubility data in highly diverse solvent systems over a wide range of experimental conditions. Read more in the Request for Information.

Jan 16, 2018

Automated Solubility Platform

Information Management for High Throughput Experimentation

ETC is seeking to solicit understanding of what end-to-end automation software platform tools are currently available that enable integration of common automation instrumentations, chemical inventory/data visualization software and storage of reaction parameters and results in a machine-readable format.

Read more in the Request for Information.

Mar 22, 2022

Jul 19, 2016

Population Balance Model

There are several opportunities to improve the current commercial PBM software in order to increase adoption. Read More about our Request for Information and submit your response. You can also read the press release.

Jul 11, 2016

Modeling Cloud

ETC is seeking a collaboration partner interested in providing accelerated access to flexibly deployed computing resources to meet member companies’ needs and enhance collaboration. Read more about our Request for Information.

Aug 21, 2017

Drying PAT

ETC is soliciting interest in collaborating with a partner on the development of a spatially resolved spectroscopy probe for application in pharmaceutical drying processes. Read more in the Request for Proposals.

Oct 23, 2017

Portable NMR Reaction Monitoring Platform

The ETC is seeking companies interested in supplying a vendor-supported portable benchtop low-field (≥ 60-200 MHz, with a footprint suitable for a standard chemistry lab hood) NMR system that can be effectively deployed for real-time analysis of reaction mixtures in process development settings.

Read more in the Request for Information.

Mar 28, 2022

HT Lipid Nanoparticle Synthesis System

The ETC is seeking companies interested in developing a high-throughput preparation platform that enables simultaneous formulation of lipid nanoparticles with different processing parameters using microfludic techniques

Read more in the Request for Information.

May 3, 2022

Pilot Plant Photochemical Reactor

ETC proposes development of a commercially available scale-up reactor that meets the needs of the pharmaceutical industry. The project involves designing, building, and characterizing a commercially available pilot-plant scale photoreactor. Characterization is expected to include light characterization (photon count and spectral irradiation) and reactor characterization (material of construction, chemical compatibility, pressure rating, mixing, residence time distribution, heat transfer, scaling factor, etc.). The unit is expected to comply with the electrical hazard rating requirements of pharmaceutical manufacturing settings and be suitable for GMP qualification. ETC members are expected to provide feedback on the initial design and may suggest revisions.

HTE Sealing Technology

The ETC is seeking companies interested to develop a reaction plate sealing technology to enable high throughput experimentation without loss of solvent after sampling. Current sealing materials are prone to losing solvent after piercing and/or swelling from being incompatible and loss of solvent effects parameters being studied including rates of reaction and solubility. The project is not limited to new compatible materials but includes new mechanisms of sampling. The sealing technology could be either a new piece of hardware (like a mechanical gate), a new piece of hardware that has a consumable part (a new device with a polymeric seal) or just a consumable part (like a mat material).