PROJECTS | ETC

ETC® Collaboration Opportunities

The Enabling Technologies Consortium regularly issues Requests for Information and Requests for Proposals to solicit interest in collaborating on high-value opportunities to deliver innovative technologies with a compelling business case. Check back regularly to see our current opportunities, or subscribe for notifications regarding new Requests for Information and Requests for Proposals.

Development of a Solid Formulation Screening Workstation

ETC is seeking a partner to collaborate on the development of a solid formulation screening workstation. Read more in the Request for Information.

Feb 24, 2021

Colonic Absorption: Preclinical Characterization for Better Translation to Humans

ETC is seeking a partner to collaborate on characterization of Colonic Absorption that can facilitate implementation of Extended Release (ER) at early phase of drug development and thereby impact overall timeline of development. Read more in the Request for Information.

Feb 24, 2021

Automated Visible Particles Analytical Instrument

ETC is seeking a partner to collaborate on the development of a visible particle analytical instrument. Read more in the Request for Information.

Jul 19, 2021

Information Management for High Throughput Experimentation

ETC is seeking to solicit understanding of what end-to-end automation software platform tools are currently available that enable integration of common automation instrumentations, chemical inventory/data visualization software and storage of reaction parameters and results in a machine-readable format.

Read more in the Request for Information.

Mar 22, 2022

Portable NMR Reaction Monitoring Platform

The ETC is seeking companies interested in supplying a vendor-supported portable benchtop low-field (≥ 60-200 MHz, with a footprint suitable for a standard chemistry lab hood) NMR system that can be effectively deployed for real-time analysis of reaction mixtures in process development settings.

Read more in the Request for Information.

Mar 28, 2022

HT Lipid Nanoparticle Synthesis System

The ETC is seeking companies interested in developing a high-throughput preparation platform that enables simultaneous formulation of lipid nanoparticles with different processing parameters using microfludic techniques

Read more in the Request for Information.

May 3, 2022

Pilot Plant Photochemical Reactor

ETC proposes development of a commercially available scale-up photochemical reactor that meets the needs of the pharmaceutical industry.

HTE Sealing Technology

The ETC is seeking companies interested to develop a reaction plate sealing technology to enable high throughput experimentation without loss of solvent after sampling.

HT Solubility Measurement Platform

The ETC is seeking companies interested in developing a robust, automated, user-friendly high throughput platform that can execute reliable solubility measurements.

Read more in the Request for Information.

Aug 26, 2022

ETC® PROPOSALS UNDER REVIEW

Sticking Assessment Tool

The ETC is seeking companies interested in developing a an empirical method/tool to quantifiably detect and assess the propensity of sticking for a given powder during the early stages of drug development with minimal material and one that is practical in complexity and accessibility.

Read more in the Request for Information.

October 20, 2022

Protein-Product Separation

The ETC is seeking information on scalable solutions that separate product from protein from typical biocatalytic reaction streams.

Read more in the Request for Information.

January 25, 2023

Co-Processing Platform
Technology

The ETC is seeking a collaborator to generate a platform co-processing technology where API and excipients are crystallized and/or precipitated in a solvent-based process and combined via various mechanisms.

Read more in the Request for Proposals

May 4, 2023

Data Curation Workbench

The ETC is seeking information from companies interested in developing a system that impacts current challenges with managing data.

Read more in the Request for Proposals

August 21, 2023

Improving IVIVC for Immediate Release Oral Drug Product

The ETC is seeking companies interested in supplying vendor-supported, commercially available new in silico PBPK/PBBM approaches in a single, user friendly software product that can be effectively used for IVIVC of IR drug products, which has not been achieved by existing software.

Read more in the Request for Proposals

November 6, 2023

Drying Kinetics Modelling

The ETC is seeking companies interested in providing better understanding of applicability of kinetic models and their use in predicting solvent content over time to support process modelling.

Read more in the Request for Proposals

November 6, 2023

Pharmaceutical Drying: Drying Scale-down Laboratory Kit

The ETC is seeking o build a lab-scale filter dryer that offers the possibility to simultaneously assess the effect of compaction force and agitation on solids being dried (i.e., with various solvent content).

Read more in the Request for Proposals

November 8, 2024

Automated Visible Particle Analytical Instrument

The ETC is seeking information from companies interested in supplying a commercially viable, automated instrument for the analysis of “visible particles” that are 100 µm and above in size.

Read more in the Request for Proposals

November 4, 2024

ETC® PROJECTS IN EXECUTION

Robust Sensors

ETC is seeking a partner to deliver a sensitive and robust in-line monitoring system that matches user requirements based upon past industry experience using LIF, XRF, and LIBS. Read more in the Request for Information.

Nov 4, 2019

Dry Modeling

The ETC is seeking a partner to develop a widely accessible module for modeling particle attrition during agitated drying. Read more in the Request for Information.

Jul 13, 2020

Organic Electrochemical Reactors

The ETC is seeking a partner to design and build lab and manufacturing scale electrochemical reactors that meet the safety, robustness and productivity needs of the pharmaceutical industry. Request for Information.

Jul 16, 2020

Dec 1, 2016

ETC® PROJECTS COMPLETED

Next-Generation Prep SFC Instrumentation

UHPLC-DAD Spectral Deconvolution

For this project ETC is seeking potential collaborators to develop UV spectral deconvolution capabilities for UHPLC-DAD instrumentation. Read more in the Request for Information.

Oct 22, 2018

Cohesive Powder Feeding Modeling

ETC is seeking a partner to collaborate on the development of a industrially implementable model for cohesive power feeding to reduce experimental work and material consumption to predict feeding performance of cohesive powders. Read more in the Request for Proposals.

Oct 7, 2020

Development and Implementation of a Powder Feeding System to Feed Poor Flowing Materials at Low Rates

ETC is seeking a partner to collaborate on the development of a industrially implementable feeding device capable of processing smaller batch sizes at low total mass flows for use during development and commercial manufacturing. Read more in the Request for Proposals.

Oct 7, 2020

Next Generation Capture

ETC is seeking a partner to deliver a module that would enable a platform to interface with wearable devices that could be worn by scientists inside laboratories to enhance and complement our ability to capture information from experiments. Read more in the Request for Information.

Dec 2, 2019

Crystal Morphology

ETC is seeking a partner to collaborate on development of a Crystal Morphology Prediction Tool. Read more in the Request for Information.

Dec 2, 2019

Compact HPLC

The ETC is seeking companies interested in supplying a viable commercial compact HPLC system. This technology, combined with existing automated sample extraction and dilution systems, would enable hood-mounted on-line characterization of chemical processes during development and scale-up in pharmaceutical, commodity, and specialty chemical laboratories. Read more in the Request for Information.

Nov 4, 2019

In this project, desired hardware and software requirements and performance criteria collected from a cross-pharmaceutical group of SFC users will be shared with potential instrument providers, in the hope of identifying partners interested in developing, optimizing, and/or commercializing the "next-generation" of preparative SFC instrumentation collaboratively. Read More about our Request for Information and submit your response. You can also read the press release.

Online UHPLC Sampler

ETC is seeking companies interested in supplying a vendor-supported online sampling system with integrated liquid chromatographic (LC) analysis employing a low volume, probe-based sampling system capable of repeated automated sampling with the ability to perform direct sample injection for LC analysis for any desired number of reaction time points. Read the Request for Information.

For this project ETC is seeking potential collaborators to develop a cost-effective, user-friendly platform focused solely on reliable solubility measurement that can be operated in “walk-up” mode to deliver accurate, reproducible solubility data in highly diverse solvent systems over a wide range of experimental conditions. Read more in the Request for Information.

Jan 16, 2018

Automated Solubility Platform

Jul 19, 2016

Population Balance Model

There are several opportunities to improve the current commercial PBM software in order to increase adoption. Read More about our Request for Information and submit your response. You can also read the press release.

Jul 11, 2016

Modeling Cloud

ETC is seeking a collaboration partner interested in providing accelerated access to flexibly deployed computing resources to meet member companies’ needs and enhance collaboration. Read more about our Request for Information.

Aug 21, 2017

Drying PAT

ETC is soliciting interest in collaborating with a partner on the development of a spatially resolved spectroscopy probe for application in pharmaceutical drying processes. Read more in the Request for Proposals.

Oct 23, 2017

ETC® Collaboration Opportunities

Development of a Solid Formulation Screening Workstation

Colonic Absorption: Preclinical Characterization for Better Translation to Humans

Automated Visible Particles Analytical Instrument

Information Management for High Throughput Experimentation

Portable NMR Reaction Monitoring Platform

HT Lipid Nanoparticle Synthesis System

Pilot Plant Photochemical Reactor

HTE Sealing Technology

HT Solubility Measurement Platform

ETC® PROPOSALS UNDER REVIEW

Sticking Assessment Tool

Protein-Product Separation

Co-Processing Platform Technology

Data Curation Workbench

Improving IVIVC for Immediate Release Oral Drug Product

Drying Kinetics Modelling

​The ETC is seeking companies interested in providing better understanding of applicability of kinetic models and their use in predicting solvent content over time to support process modelling.

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Pharmaceutical Drying: Drying Scale-down Laboratory Kit

Automated Visible Particle Analytical Instrument

ETC® PROJECTS IN EXECUTION

Robust Sensors

Dry Modeling

Organic Electrochemical Reactors

ETC® PROJECTS COMPLETED

Next-Generation Prep SFC Instrumentation

UHPLC-DAD Spectral Deconvolution

Cohesive Powder Feeding Modeling

Development and Implementation of a Powder Feeding System to Feed Poor Flowing Materials at Low Rates

Next Generation Capture

Crystal Morphology

Compact HPLC

Online UHPLC Sampler

Automated Solubility Platform

Population Balance Model

Modeling Cloud

Drying PAT

Co-Processing Platform
Technology

The ETC is seeking companies interested in providing better understanding of applicability of kinetic models and their use in predicting solvent content over time to support process modelling.