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Solubility Prediction of Multicomponent Crystals
The ETC is seeking a practical, scalable, and scientifically robust computational tool for the prediction of solubility in multicomponent crystal systems, particularly salts and cocrystals, with sufficient predictive capability to reduce reliance on extensive experimental screening and support more efficient pharmaceutical discovery and development.
The scope of work listed in the RFI highlights the open questions identified by the Solubility Modeling Working Group in the area of in-silico solubility prediction of multicomponent crystals. Interested parties are welcome to respond to any number of the sections below, especially if their expertise can only address certain sections or a portion of a given section.
Download the Request for Proposal and submit your response
RFI ISSUED: June 30, 2026
QUESTIONS on RFI DUE to ETC: July 21, 2026
RFI RESPONSES DUE to ETC: August 21, 2026
Q&A - Note see FAQ document for answers to common questions
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